有阻塞性肺炎、肺不张,肿瘤有增大,确实需要联合用药才能解决炎症问题了。 * u* x2 D6 |: e/ S% o% t % T1 ^. \# a. a! P F0 ]" n阿瓦不敢上,力比泰、铂类以前都用过许多次了。0 Y) l1 M0 v' |' y$ h
我倒是觉得2992才用了几天现在放弃可惜了。# }& h% e+ n. D8 N3 _. Y7 s
是否可以考虑2992联合化疗?* t: S% L# d6 L% l4 b6 b d& W
看见美国的正在进行的2992联合化疗的临床试验。贴上来供楼主参考。) @0 ?8 R% w6 I6 [ n( F
1,2992+紫杉醇,有好几项三期临床试验在进行。 ! L, h* @% y4 z& S- y其中一项:9 b k }1 Q6 d
BIBW 2992 (Afatinib) Plus Weekly Paclitaxel Versus Investigator's Choice of Single Agent Chemotherapy Following BIBW 2992 Monotherapy in Non-small Cell Lung Cancer Patients Failing Erlotinib or Gefitinib ; S6 W3 X. L5 b$ ]" P& qDrug: BIBW 2992 8 v4 P/ H& B/ F; S; A, jBIBW 2992 in a dose of 40 mg/day in combination with Paclitaxel to explore safety and efficacy versus investigator´s choice of chemotherapy + ^/ c) R- i+ A0 D+ c& \
2,2992+力比泰,是一期临床。4 @4 R5 u% R; w- M) j& v/ U3 a
BIBW 2992 (Afatinib) in Combination With Pemetrexed in Advanced Solid Tumours 7 u. A% X6 M0 X& p' d + q" I! U9 S/ {6 X1 V- N( G; v, D& n3 S# N