刚下了avastin官网的用药指南:
1 J7 R7 I2 L1 \! N1 S5 J% U5 F- Z9 H [1 j
Patients should continue treatment until disease progression or unacceptable toxicity. * m" v$ R% W) N! W2 ]
1 Metastatic Colorectal Cancer (mCRC) 2 A9 G' ^' b9 e: ~) H
The recommended doses are 5 mg/kg or 10 mg/kg every 2 weeks when used in combination with 1 |5 x0 a! B/ B6 r
intravenous 5-FU-based chemotherapy.
( P7 X# L. E8 h2 Q& v8 I• Administer 5 mg/kg when used in combination with bolus-IFL.
8 W8 v) e& l6 [% t/ L( ~) k• Administer 10 mg/kg when used in combination with FOLFOX4.
% c) ~! R- H0 R' K9 F1 R0 i' j) ^' S2 Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
7 O4 V( H9 m3 n+ y The recommended dose is 15 mg/kg every 3 weeks in combination with carboplatin and " y) `# L) ]- r S& ?
paclitaxel. 2 [$ a. ` k, r% ?; J
3 Metastatic Breast Cancer (MBC)
% @: ]' B: d' [ The recommended dose is 10 mg/kg every 2 weeks in combination with paclitaxel.
3 J9 s e1 b H4 Glioblastoma
4 C. j- m5 N" _ The recommended dose is 10 mg/kg every 2 weeks.
! ` r+ w- L+ K! S% k2 u5 Metastatic Renal Cell Carcinoma (mRCC)
1 O% v7 W! z+ i' W4 W& t& g$ O The recommended dose is 10 mg/kg every 2 weeks in combination with interferon alfa. 5 z. ]0 m4 G7 }5 }' O6 n# X
% N8 U) c) }3 g! y# I9 N/ F按照这个说明非小细胞腺癌的服用剂量是15mg/kg,与卡铂紫杉醇合用,avastin每三周用一次。
5 L; J0 e. t5 i% L0 S1 p6 z- G我妈妈是肺腺癌转肝,体重53kg,现在医生联合卡铂紫杉醇化疗了一个疗程21天。 但avastin不是一次注射的,每7天注射一次200mg,一个疗程21天注射了3次(分别是第一、八、十五天) |